What is one of the main challenges faced when using embryonic stem cells?

One of the main challenges faced when using embryonic stem cells revolves around ethical concerns related to embryo destruction. This issue arises because the process of obtaining embryonic stem cells typically involves the destruction of an early-stage human embryo, leading to significant moral and ethical debates. Various groups argue about the rights of the embryo and whether it should be considered a human life, complicating research and funding efforts in this area of biomedical engineering. This ethical dilemma has led to restrictions and regulations in many countries regarding the use of embryonic stem cells, making it a critical challenge in advancing research and clinical applications.