Apilgraf is primarily composed of which substances?

Apilgraf is primarily composed of keratinocytes and collagen. Specifically, it utilizes keratinocytes derived from neonatal foreskin, which are critical for wound healing as they play a significant role in skin regeneration and repair. The collagen component comes from seaweed, which is used because it provides a similar structure and biocompatibility needed for effective integration into the human body. The unique combination of biological materials in Apilgraf makes it suitable for promoting healing in chronic wounds and burns.

In contrast, the other options do not accurately reflect the composition of Apilgraf. Dermal fibroblasts and artificial collagen do not comprise the primary components; while collagen and elastin from animal sources are also not correct, as Apilgraf specifically uses collagen from seaweed for its structure. Finally, a formulation that includes only synthetic keratin and growth factors overlooks the importance of the biological materials derived from neonatal foreskin. Thus, the correct answer effectively captures the essential components of Apilgraf and their significance in biomedical applications.