True or false: A biomaterial should NOT interact with the body.

The assertion that a biomaterial should NOT interact with the body is often too simplistic. In reality, the interaction of biomaterials with biological systems varies based on the intended application. Biomaterials are designed with specific roles in mind, which can range from serving as implants that support tissue regeneration to drug-delivery systems that rely on interactions with cells and tissues to effectively release therapeutic agents.

In many scenarios, appropriate interactions are essential for functionality. For instance, a scaffold used in tissue engineering must interact with surrounding cells to promote adhesion, migration, and growth. Similarly, a biomaterial designed for controlled drug release must interact with the biological environment to ensure the drug is delivered at the right rate and concentration. Therefore, whether a biomaterial interacts with the body depends significantly on its intended use, emphasizing that a modular approach to biomaterial design and interaction is crucial in the field of biomedical engineering.