What is done with harvested bone marrow stem cells in tracheal regeneration?

In the context of tracheal regeneration, harvested bone marrow stem cells are placed in a bioreactor with a scaffold as a key step in facilitating tissue engineering. This process is vital because it allows the stem cells to proliferate and differentiate in an environment that mimics the conditions of natural tissue growth.

The bioreactor provides the necessary nutrients, growth factors, and ideal mechanical conditions that stimulate the stem cells to mature into the desired cell types needed for rebuilding the tracheal structure. The scaffold serves as a physical support where the cells can attach, grow, and develop into functional tissue. This approach is crucial for ensuring that the cells and resulting tissue can integrate properly with the surrounding biological environment, providing a viable solution for tracheal repair or regeneration.

Using this method, researchers can enhance the potential for successful integration of the engineered tissue with the patient's existing trachea, which is a significant factor for long-term recovery and function.